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| Technology |
Porcine Transmissible Gastroenteritis Virus Oral Vaccine Production In Plants |
| Description |
This invention provides a method of preparing at least one porcine Transmissible Gastroenteritis Virus (TGEV) protein comprising the steps of obtaining the S gene of TGEV that has been altered for optimal expression in plants. |
| Inventors |
Éva Nagy, Tamás Tuboly, Wenjin Yu, and Larry Erickson |
| Patent Status |
Canadian and U.S patents filed. |
| Scientific Merits |
This invention involves the development of a vector with the S gene insert, suitable for transforming plants, and selecting the plant. It also provides a method of immunizing pigs against porcine TGEV comprising of harvesting the transformed plant to obtain harvested tissue and feeding the harvested tissue to pigs, or extracting the protein from the harvested tissue and administering the protein to pigs as a feed supplement or as an injection. Direct grazing of the plant tissue by pigs prior to harvesting may also be employed as desired.
NOVELTY / BENEFITS
·S gene for TGEV that has been altered for optimal expression in the plant
·Vector comprising the S gene
·Method for oral vaccination of pigs against TGEV |
| Development Status |
Prototype developed. |
| Competitive Advantage |
Alternative method for vaccinating pigs against TGEV has been developed. This invention has the potential of using transformed plants as the biological material for the vaccine. |
